Endocrine Abstracts

Carcinomas are the third most frequent cause of complications in acromegalic patients. It has been suggested that diabetes potentiates the risk of cancer. To assess the frequency and type of malignant neoplasms in acromegalic patients and control group; to evaluate, in both groups, the relationship between IGF-I/GH and the development of cancer, and between glucose metabolism and cancer in two centers of Buenos Aires, Argentina. Retrospective, cross-sectional study; medical re...

Nonfunctioning pituitary adenomas (NFAs) have no symptoms of hormonal overproduction and can be asymptomatic or have severe symptoms due to mass effects. The aim of our study was to assess clinical features and therapeutic outcomes in patients with clinically NFAs. We retrospectively collected data of 175 patients from 3 hospitals of Buenos Aires. Mean age: 51 years (r:13–90), 52% women, mean follow-up: 7.37 years. At diagnosis, clinical presentation was: visual field def...

Giant prolactinomas are tumors with a large size >4 cm and/or prolactin levels higher than 3000 ng/ml and/or highly invasive growth. Today dopamine agonists (DA), mainly cabergoline (CAB), are the first-line choice in the treatment of these tumorsTo assess the efficacy, safety and long-term follow-up of patients with giant prolactinomas treated with DA. We retrospectively reviewed the clinical records of 33 patients with giant prolactinomas. Mea...

Craniopharyngiomas are rare lesions derived from cell remnants of Rathke’s pouch, usually localized in the sellar and suprasellar areas.Objectives: To analyze clinical, endocrine and histological features in a group of patients from Buenos Aires city. To assess efficacy, number of surgeries and complications after surgery or other treatments.Material and methods: Multicentric, retrospective, transversal study. Adult patients w...